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Photo of Karl Barry Sharpless

Photo: Bengt Oberger / CC BY-SA 4.0 (source: Wikimedia Commons)

Karl Barry Sharpless

American chemist

April 28, 1941 (age 85) · Philadelphia, Pennsylvania, United States

  • Pennsylvania
  • chemist
  • university teacher

Karl Barry Sharpless is a chemist and university teacher. Karl Barry Sharpless was born in Philadelphia, Pennsylvania, United States on April 28, 1941. That works out to 85 years old in 2026. Schooling on record includes Harvard University. Recorded honors include ACS Award for Creative Work in Synthetic Organic Chemistry, (1983), Guggenheim Fellowship (1987), Prelog Medal and Lecture (1988) and 5 more.

My Take

Sharpless sits in rare air for me: a two-time Nobel laureate, decades apart, in genuinely different territories. Chirally catalyzed oxidation in 2001 and click chemistry in 2022 aren't refinements of one idea but two separate intellectual leaps, which says something profound about how freely his mind roams. What I respect most isn't the trophy case, long as it is, but his instinct to turn chemistry into usable tools. Click chemistry now powers drug discovery and materials science worldwide. That's a scientist who didn't just publish, he reshaped how others work. I find that kind of legacy far more inspiring than any single award.

1. Profile

Name (English)
Karl Barry Sharpless
Name (Japanese)
バリー・シャープレス
Reading
ばりー・しゃーぷれす
Born
April 28, 1941 (age 85)
Zodiac / Chinese zodiac
Taurus / Snake
Origin
Philadelphia, Pennsylvania, United States
Occupation
chemist / university teacher

2. Background

University
Harvard University

Awards & achievements

  • 1983 ACS Award for Creative Work in Synthetic Organic Chemistry,
  • 1987 Guggenheim Fellowship
  • 1988 Prelog Medal and Lecture
  • 1991 Scheele Award
  • 1992 Arthur C. Cope Award
  • 1993 Centenary Prize
  • 1995 King Faisal International Prize in Science
  • 1998 Harvey Prize

4. About this entry

Tags

  • Pennsylvania
  • chemist
  • university teacher
Last updated
2026-06-21

Facts are limited to publicly available information up to 2024; non-public or unconfirmed items are omitted. English text is machine-assisted (facts translated by Sonnet, "My Take" written by Opus 4.8). The Japanese page is the source of record.

Frequently asked questions

When was Karl Barry Sharpless born?

Born April 28, 1941 (age 85).

Where is Karl Barry Sharpless from?

Karl Barry Sharpless is from Philadelphia, Pennsylvania, United States.

What does Karl Barry Sharpless do?

Karl Barry Sharpless works as chemist, university teacher.

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